Using FENTORA

How to take FENTORA

Peel it.
- Keep tablets in blister packs until ready to use. Do not store in pillboxes
- Separate one of the blister units from its blister card by bending and tearing apart at the perforations
- Bend the blister unit along the line where indicated
- Peel back the foil on the blister pack to expose the tablet
- Do not push the tablet through the foil because this could damage the tablet
- Do not attempt to split the tablet
Place it.
- Immediately place the FENTORA tablet in your mouth. Place it above a rear molar tooth between the upper cheek and gum
- Your doctor may instruct you to switch sides of the mouth with each new tablet used
- Do not bite, chew, or suck FENTORA tablets. If you do so, you will swallow more of the medicine before it can cross the lining of your mouth, and you may get less pain relief for your breakthrough cancer pain
Feel it.
- Leave the FENTORA tablet in place until it dissolves. This may take about 14 to 25 minutes. As the tablet dissolves, you may feel a slight bubbling sensation between your cheek and gum
- If there is any tablet remaining after 30 minutes, swallow it with a glass of water

Keep FENTORA out of the reach of children

Keep FENTORA in a safe and secure place away from children and anyone to whom it has not been prescribed. If a child accidentally takes FENTORA, call 911 or call emergency help right away

Keep tablets in their blister packages until you are ready to take FENTORA. Do not store FENTORA in pillboxes. Once a blister is opened, the tablet must be taken immediately

Finding the right dose to relieve your breakthrough pain

To start you on FENTORA, your doctor will likely prescribe you a low dosage strength. This initial dose may include more than 1 tablet (see Situation 1 below)
Next, your doctor may gradually increase the dosage strength of FENTORA to find the right dose for you. To help with this process, your doctor may instruct you to use multiple tablets at the same time (see Situation 1 below)
You must wait at least 4 hours before taking FENTORA for another flare of breakthrough pain
- Do not treat more than 6 flares in a single day
Once you are on a regular dose of FENTORA, you should generally use only 1 FENTORA tablet per breakthrough pain flare
FENTORA comes in multiple dosage strengths (100 mcg, 200 mcg, 300 mcg, 400 mcg, 600 mcg, and 800 mcg)

If you still have pain 30 minutes after taking a single dose

If your pain is not relieved within 30 minutes, your doctor may instruct you to take only 1 additional dose of the same strength for that flare. Please note, no more than 2 doses should be used per breakthrough pain flare (see Situation 2 below)

IMPORTANT:

Do not use FENTORA unless you are regularly using other opioid pain medicines around-the-clock for your constant cancer pain and your body is used to these medicines.
Keep FENTORA in a safe place away from children. Accidental use by a child is a medical emergency and can result in death. If a child accidentally takes FENTORA, get emergency help right away.

Read the Medication Guide that comes with FENTORA before you start taking it and each time you get a new prescription. There may be new information. This Medication Guide does not take the place of talking to your doctor about your medical condition or your treatment. Share this important information with members of your household.

The most important information you should know about FENTORA is:

FENTORA can cause life-threatening breathing problems which can lead to death:
- If you are not regularly using other opioid pain medicines around-the-clock for your constant cancer pain and your body is not used to these medicines. This means that you are not opioid tolerant
- If you do not use it exactly as prescribed by your doctor
Your doctor will prescribe a starting dose of FENTORA that is different than other fentanyl containing medicines you may have been taking. Do not substitute FENTORA for other fentanyl medicines, including Actiq^®, without talking with your doctor.